i just had a 5" exhaust installed on my truck. i did the muffler delete, wow that was a mistake cause the drone is crazy. i will be putting the muffler back on. i have no complaints other than that about the system and im waiting for my truck to get back out the shop to install my tymar intake.
if your going to chip your truck you might need to free up the intake and exhaust some to keep egts in check maybe.
maybe someone with more knowledge will chime in, good luck with what ever route you choose