It's be theorized that the injection systems don't respond well above 3200 PSI with most systems actually working better at about 2900-3000 PSI. Part of the reason is that the poppets on the injector start floating at some point and don't allow proper injection function.
Most tuners generally limit ICP to about 3000 PSI at WOT. However, at cruise your ICP is closer to about 1600-1800 PSI so the whole over-pressurization issue becomes fairly moot. That is unless you're commanding 3600 PSI at cruise.
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