what injectors to go with?

[widieseltech]

im looking at putting different injectors in my truck like some single shots or hybrids i dont want anything to crazy just a little bigger then stock and better mpgs any good brand or sizes out there? i was looking at swamps or beans diesel. Is there any certian brand that bill knows how to tune better or that he may prefer? i have a 2000 f250 ccsb with a gryphon cs w/40,tow 80dd,120perf, intake and 4" exhaust and 35'' tires
i was looking at going hybrids just for the fact that they will run better on a stock hpop since they use less oil to fire. i know my tunes will have to be changed for them. just wondering how much to rewrite the tunes?

also do i need to have my tunes redone if i just put a 38r on my truck?

any help would be great. thanks guys