Custom tune with plans on upgrading tires

[ssrider]

I have a 2005 f150 5.4 with a K&N CAI and MBRP exhaust. I'm looking to order a gryphon with custom tunes but I currently have stock tires and plan on upgrading to 33's in a couple months. Would it be better to get the tunes written for the 33's and then adjust the TS down until I get the tires? Or is it better to get the tune written for my current tires and then adjust the TS up for my new tires later? Also is there any harm in using the canned towing tune with these mods or should I also have a custom towing tune written?

Thanks