Like I said, I have heard both ways on compatibility in the fuel system, there are many sites that swear by it and sell components to convert (computers, not fuel systems). I understand the energy difference in E85 but it would still be a nice option in the event of a gas spike where E85 stays low. I don't know the validity of it but I have also heard that E85 has a smoother power curve and is good for towing. I don't have any first hand experience with E85 which is why I am asking. If a tune is enough to make it work then for 30 bucks I wouldn't mind giving it a try.
Phq, thanks for making me feel like I'm not crazy

I know I've read it all over that the fuels systems are fine, I wish I could find a definitive answer.
The wife semi-OK'd the jump to an F250 .. so if I play my cards right I will be asking diesel questions instead in the near future.