you will not have any longevity problems with Bill's tunes, Hopefully Cody will jump in as he is real good with the Manual Tranny trucks. That being said you have avoided the real Achilles heel which is the auto trannys. I have about 35K on a Phoenix chip and that is with my modified versions of Bill's tunes... mostly some altitude mods... 175K on the truck and no problems at all. I have towed up to 21K lbs with my truck on the 40HP tow tune with no EGT issues at all. They are busy plus Corey is getting ready to have surgery and several of us Moderators have been busy with other things in our lives so I apologize you have had to wait for a response but there is definitely no increased risk of damage to yr 7.3 with appropriate tunes installed. Now if you had a 6.0 I would definitely recommend some mods before doing any type of power increase.. as for your 7.3 go for a 4" or larger turbo back exhaut and a set of gauges. THe 6637 filter mod is great.. I have that on my truck too. you can also do the Zoodad mod to get more direct cold air flow to your filter if you want. I would get the Phoenix or FU setup for a 7.3 shift on the fly is much better than stopping and taking a few minutes to reprogram the CPU with a programmer like the CS
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DJ Phoenix (my modded) Hi-1200/240Tow/75FS/80DD/100/140SS +Minotaur
ASE Master Auto Technician 
2001 Ford Excursion 7.3 4x4
Projects. 1970's Hustler and Max II Amphibious ATV's
Last edited by soutthpaw; Sun, June 13th, 2010 at 11:47 PM.
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